The “handcuff-model” of cohesin trapping sister DNA.

The accurate separation of sister chromatids into daughter cells is critical for maintaining genome integrity. The mechanism by which replicated sister chromatids are accurately segregated into daughter cells is termed cohesion.  An alternative model proposed of  how cohesin physically holds chromatids together is the two-ring ‘handcuff’ model in which each sister is encircled by one cohesin ring and two rings then associate with each other or interconnect resulting in cohesion of DNA strands. 

Info
Client:

Commissioned work.

Software used:

Adobe Illustrator, Adobe Photoshop.

URL:

Category:

Illustrations

Date:

November 13, 2017